Over time, most populations went extinct, allowing the genes of only a few groups to proliferate, further erasing genetic diversity.
If the Swan River becomes more nutrient polluted and subsequently more algal dominated, then this ubiquitous invader may proliferate further, with difficult-to-predict system-wide ecological and biogeochemical consequences.
That sound proliferated further with the rise of Yung Lean and his stable of producers like Yung Sherman, who introduced trance-synth elements to the mix (themselves riffing on Araabmuzik's 2011 album Electronic Dream).
These results further support a model wherein caspase-3 is upregulated transiently during the proliferation of recently activated CD8+ T cells, and this apoptotic-like phenotype is progressively lost as cells proliferate further, and differentiated effector cells emerge.
Coincidently, upon passaging of the reprogrammed cells, a further upregulation of TP53, CDKN1A, CASP3 and CASP9 was observed, which may have resulted in the cells inability to proliferate further.
This process appears to involve the commitment of the mammary stem cells to either a luminal (CK18+) or a myoepithelial (CK14+) differentiation pathway through a series of coordinated events that precede the ultimate loss of an ability to proliferate further.
In control group, small polyps proliferated further to become large polyps.
Radiation treatment also inducts DNA double strand breakage in cancer cells and thus blocks their ability to proliferate further [ 3, 4].
The asymmetric expression of ceh-20 in seam daughters suggests a model in which CEH-20 and UNC-62 repress rnt-1 in anterior daughters destined not to proliferate further.
The objective of genotoxic therapy is to induce irreparable genetic damages preferentially in the fast growing cancer cells, so that they will undergo cell death or permanent cell cycle arrest through DDR signalling, thus blocking their ability to divide and to proliferate further [28].
