Sentence examples for proliferating effect from inspiring English sources

However, overproduction of polyamines may contribute to malignancy due to their cell proliferating effect and the oxidative stress caused by polyamine oxidase37.

Oestrogens have, by means of the ER, a proliferating effect on breast cancer cells.

Serum IL-6 was measured using a specific bio-assay based on the proliferating effect of IL-6 on 7TD1 hybridoma cells.

Genes that are co-expressed with several oncogenes may prove to be useful targets in countering the proliferating effect of these genes in tumours.

Disruptive innovation, therefore, can have a proliferating effect.

The activation of MAPK/ERK1/2 signaling pathway was demonstrated to enhance the growth of epithelial cancer cells, in particular, bladder cancer and HNSCC, which explains why the ANO1 mutant has lost the proliferating effect.

This contribution deals with the questions, from which sites CGRP is released, where it is drained and where it acts to cause its headache proliferating effects in the trigeminovascular system.

In addition, upregulation of CXCR7 induced cell cycle progression while depletion of CXCR7 arrested the G0/G1 to S phase transition, which could partially explain the CXCR7-induced proliferating effects.

Not only did the parabens trigger the estrogen receptors by turning on genes that caused the cells to proliferate, the effect was significant.

Furthermore, as diffuse infiltrative glioma cells may show limited proliferative activity, and virus replication occurs preferentially in proliferating cells, the effect of virotherapy on the diffuse infiltrative part of gliomas remains to be elucidated [ 48, 159 , 167.

Recently, it has been shown that shortening of 3′ UTRs by alternative polyadenylation (APA) alters protein expression in proliferating cells, an effect partly attributed to the loss of miRNA binding sites (Sandberg et al. 2008; Mayr and Bartel 2009).