The Panel strongly endorsed endocrine therapy alone as neoadjuvant treatment for postmenopausal patients with strongly positive hormone receptors and low proliferating disease, and most thought that such treatment should be continued until maximal response.
After 35 days of treatment (day 42 of the study) proliferating disease was observed in all of the vehicle treated animals, while 5 of the 9 drug treated animals showed no detectable luminescence.
Other threats have proliferated - disease, famine, environmental degradation and migration - that transcend state borders.
We therefore chose this time point to initiate p(I C) treatment which was repeated every 4 days in order to efficiently target this highly proliferating ALL-like disease (scheme in Fig 3B).
Chronic diseases are proliferating around the globe, affecting ever more people here in the U.S. and taking hold at ever younger ages.
As with behavioral disorders, the social mechanism of transmission may underlie drug-use initiation, continuation, and transition such that those activities then mimic infectious disease patterns, proliferating through the population until some natural threshold or intervention prevents further spread.
These deer also bring us proliferating ticks and Lyme disease.
As ocean temperatures rise and oceanic diseases proliferate, species like sea stars struggle to survive, and scientists are looking for underlying causes.
As species diversity declines and animals and plants face the threat of extinction, diseases proliferate, pollution increases, and food resources dwindle.
Clinical studies of childhood diseases proliferated throughout the 18th and 19th centuries, culminating in one of the first modern textbooks of pediatrics, published by Frédéric Rilliet and Antoine Barthez in France in 1838 43, but there was little that could be done to cure these diseases until the end of the 19th century.
Development of cell-based therapies is rapidly proliferating in a number of disease areas, including musculoskeletal disorders.
