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Our data indicate that miR-188 expressed cells have slower growth and cell proliferate rate.
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The cells with over-expression Trip13 have a slower proliferating rate than controls, meaning that increased proliferation in Trip13 over-expressors cannot account for observed increases in cell number after stress.
HIF2α enlarged cells also displayed a reduced proliferating rate associated with a diminution in p42/44 MAPK phosphorylation, while proliferation and phospho-p42/44 phospho-p42/44 in small HIF2α(1–485) cells.
The result represents the percentage of proliferating rate in either β-cells or ductal cells.
The rate of the BrdU positive cells was 2.61% in the non-irradiated tumors on average, whereas the proliferating rate was 0.93% in the irradiated lung tumor samples.
In order to maintain their high proliferating rate, cancer cells require an elevated production of cellular membrane components membrane such as cholesterol and phospholipids [47], [48].
Mayr and Bartel found that expression of mRNAs with shortened 3'UTRs are more apparent in transformed cells than nontransformed ones with similar proliferating rate [31].
Mayr and Bartel further found that 3'UTR shortening is more apparent in transformed cells than nontransformed ones with similar proliferating rate [31].
Caco-2 intermediate adenoma cells had the slower proliferating rate and doubling time of 39 h.
Thus, the low proliferating rate of Th17 clones could contribute to their resistance to activation of the cell death machinery.
The high proliferating rate of cancer cells forces them to produce more energy but also more macromolecules.
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