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More recently, however, it has become clear that adult stem cells are not universally quiescent but instead cycle in accordance with the needs of the tissue: Some types of stem cells proliferate continuously, whereas others switch from quiescence to rapid proliferation in response to certain stimuli (e.g. wounding or hormones) (Wabik and Jones, 2015).
In the case of BCR-ABL, the signal generated tells the myeloid cells to proliferate continuously.
These five cell lines could proliferate continuously for more than one year.
The acquired capabilities of tumor cells include their ability to proliferate continuously ignoring apoptosis or growth-inhibitory signals, generating their own mitogenic signals.
Induced cells that could proliferate continuously for approximately two months (60 days) were subsequently cultured in the absence of OP9 cells and in the presence of hematopoietic humoral factors (Table 1).
Once the PGCs reach the gonadal anlagen at about 8.5 days post-coital (dpc), the PGCs proliferate continuously until they enter meiosis, after which the cells are referred to as oocytes [2], [3].
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Porous β-Ca2SiO4 ceramic scaffolds displayed a good biocompatibility, since human osteoblast-like MG-63 cells and goat bone mesenchymal stem cells (BMSCs) proliferated continuously on the scaffolds after 7 d culture.
The 21 day-monitoring through the use of MTS assays and SEM analyses demonstrated that human mesenchymal stromal cells (hMSCs) remained viable on PHB/nHA biocomposite scaffolds and proliferated continuously until reaching confluence.
F3-effluc cells proliferated continuously until day 8 in the stiff GPT 5.8 K as well as in the soft GPT 1.8 K. Figure 2 Three-dimensional culture of human neural stem cells, F3-effluc, within the soft and stiff GPT hydrogels.
In the contemporary world, especially developing countries, the demand for electricity is proliferating continuously and power is not only a criterion for fulfilling the requirement, but it is also the responsibility of engineers to provide the reliable and stable power to the consumers in a satisfactory manner.
Furthermore, the IR and IGF-IR substrates IRS1 and IRS2 were not tyrosine phosphorylated in cells proliferating continuously in serum-free and insulin/IGF-I-free media.
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