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Rather, we found that most dopamine neurons (besides TS-projecting dopamine neurons) have similar inputs regardless of their projection target.
The main projection target of midbrain dopamine neurons is the striatum.
Margolis, E. B., Mitchell, J. M., Ishikawa, J., Hjelmstad, G. O. & Fields, H. L. Midbrain dopamine neurons: projection target determines action potential duration and dopamine D2 receptor inhibition.
In our new study, led by Mitsuko Watabe-Uchida, (Menegas et al., 2015), we labeled the inputs to dopamine neurons based on their projection target.
Similarly, the projection target matrix was also reduced to 2D.
We generated the gene expression correlation matrix and the projection target correlation matrix from the injection site gene expression and projection target data matrices, respectively.
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It was indeed the same color-coding as in Figure 7. Reviewer #2: 1) Parts of the results need more explanation: a) At the very end of the section titled Distribution of dopamine neurons projecting to different projection targets.
In this study, we examined dopamine subpopulations that project to eight different projection targets.
These groups also found that dopamine neurons with different projection targets have similar inputs, although none of them examined dopamine neurons projecting to the tail of the striatum.
Location of cell bodies in V1 as a function of their projection targets.
Pyramidal cells occupying these two regions differed in their long-range inputs, local wiring, projection targets, and electrophysiological properties.
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