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These results suggest that GPs may not have methods available to sufficiently consider severity of disease and projected prognosis given particular treatment decisions.
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P45 appears as one of the wrongly projected poor prognosis patients instead of P55.
The methods for exposing impacted canines are outlined and the relative merits of using a closed versus open surgical procedure are discussed in relation to the projected long-term prognosis and appearance of the treated outcome.
LHZ participated in design therapy project, estimate prognosis of the two patients.
Exclusion criteria included: 1) a terminal prognosis, 2) a projected stay of less than 90 days, or 3) health complications that prohibited contact.
The planned timeline for this effort spans 5 years (beginning October 2011), and includes milestones for the completion of project 1 (epileptic encephalopathies) by the end of year 3 and project 2 (multiplex families and pairs) by the end of year 5. Completion of project 3 (prognosis) will depend on extra funds being obtained.
Alternatively many good-prognosis patients are projected to the central regions using List A but are scattered around the edges using list B: for example P362, P248 which give very high confidence of being good prognosis patients while list A does not give such high confidence of P362 and in addition, misclassifies P248.
For List A from Figure 1, good prognosis patients are likely to be projected towards the top of the visualisation map while the poor prognosis patients are at the bottom.
However, with List B it is not as unambiguous since this patient is projected into the interface between the two prognosis groups.
For LLE, there are 4 poor prognosis patients (in both gene sets) who are projected to the wrong cluster.
Already, the prognosis has gone from grim to grimmer: the comptroller's office now expects the city to lose 165,000 jobs by August 2010, about double what it projected at midyear.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com