Even so, inefficiencies may be prohibitively high, and challenges significant.
One method currently used is to show that homologous recombination leading to gene inactivation only occurs in the presence of a second copy of the gene, but obtaining statistically significant data can be prohibitively difficult.
Such a trial is unlikely to take place, however, because of questionable ethics and because the sample necessary to detect a significant difference would be prohibitively large.
Still, the cost per genome was considered prohibitively expensive for clinical use, indicating that significant technological challenges remained before genome research could be incorporated into routine health care.
Priscilla Linn, Belfast, Me.: I absolutely agree with your premise that oil must become prohibitively expensive so the crisis will be significant enough to warrant attention from the government.
Routine VL monitoring in resource-limited settings requires significant infrastructure and expertise and remains prohibitively expensive in most settings.
This unparalleled resolution in methylation detection is transforming the field of epigenomics; however, adopting these genome-wide approaches requires significant bioinformatics expertise and may be prohibitively expensive for certain applications given their low throughput.
CCS has not, however, been deployed on a significant scale and has proven to be prohibitively expensive for energy companies to operate.
Therefore, this variability in the geometric and material properties of cadaveric specimens often requires prohibitively large sample sizes in order to detect statistically significant differences in implant performance.
No matter how much the team liked the Oxanthera neo-caledonica's peel aroma, everyone on the trek knew that growing enough of the fruit to extract commercially significant quantities of its essential oil would be prohibitively expensive.
However, genotyping significant numbers of individuals with large number of SNPs remains prohibitively expensive for many research groups.
