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For example, the uptake of a large, micrometer-size carrier may exceed cellular endocytic capacity; formation of such a large vacuole would require prohibitively extensive mobilization of cell membrane and cytoskeleton.
To address the full complexity of genetic and non-genetic factors affecting healthy ageing across the full range of geographical and ethnic diversity within the UK would be prohibitively extensive and expensive.
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In Sweden, the fairly egalitarian wage structure makes nannies and au pairs prohibitively expensive, while the extensive public child-care system is mainly geared for parents keeping office hours--something that doesn't apply to most academics.
In practice, though, acquiring one is impossible in some cases and prohibitively expensive in others, due to obscure zoning rules and the extensive waiting periods needed for various government agency sign-offs.
Because of their illegitimate birth, their father considered the girls unmarriageable, if not posing problems of prohibitively expensive support or dowries, which would have been similar to Galileo's previous extensive financial problems with two of his sisters.
Extensive sampling is typically required, but in most cases, field sampling is prohibitively expensive and limited by terrain.
Prohibitively expensive.
The tickets are prohibitively expensive.
Commercial distribution remains prohibitively expensive.
Flights were complicated and prohibitively expensive.
But that would be prohibitively expensive.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com