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While also suffering from prohibitive running times, it is worth noting that this latter algorithm also proposes a seedless approach to the RNA secondary structure design problem.
Mapping of short reads on long reads provides sufficient coverage to eliminate up to 99% of errors, however, at the expense of prohibitive running times and considerable amounts of disk and memory space.
A small sub-graph in a simple graph structure can return no SNPs and a sub-graph in a very complex structure has a prohibitive running time, there is no algorithmic bound.
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Typical formulations suffer prohibitive run times even on medium-sized problems with less than 30 tasks.
The lop-sided result was partly attributable to a prohibitive run of injuries, with six players forced to leave the tour early during the protracted seven-match series, as the effects of a long tour took hold.
It is also prohibitive to run voter identification operations or advertise everywhere a candidate might be competitive.
It's prohibitive to run analyses on thousands of groups of homologs, such as in multiple sequence alignment, phylogenetic tree reconstruction and fitting of distinct codon evolutionary models to the data, using single processor software within a feasible time frame [ 17].
The product will be fairly cost prohibitive at launch – running around $4,500, a price that will likely confine early usage to rehabilitation centers, wherein the patient can utilize the brace under the supervision of a doctor.
He spoke about how, despite the prohibitive costs of running the island, nothing could prevent him from focusing all his energies on his fabricated paradise.
A GA with an attached simulator is a long and complex computational task and it requires a prohibitive amount of running time on a single CPU machine.
115 eQTL studies are generally characterized by large numbers of phenotypes (e.g., the number of transcripts on a microarray), but the mapping is typically performed with fewer individuals, due to the still prohibitive cost of running the arrays.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com