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The AR proliferative response program has been well studied, but its prohibitive response program has not yet been thoroughly studied.
Out data provide a valuable data set in understanding the molecular basis for the growth prohibitive response program of the AR in advanced prostate cancers.
We have identified a lower percentage of AR binding regions contain the AR consensus site, probably due to the stringent criterion we used, or suggesting that the AR binding consensus for the prohibitive response in PC3-AR cells is different from that of the proliferative cells such as LNCaP cells.
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"Usually, network television isn't a place to go because the efficiencies are cost prohibitive for direct-response advertisers to go there," said Richard Gagnon, the chief media officer of the advertising agency Draftfcb.
The symmetric magnitude responses are too prohibitive for applications.
However, due to its single-carrier nature, SC-FDMA performance degrades in channels with long impulse responses and becomes prohibitive to equalize when implemented in time domain (TD).
Both [9] and [10] equalized SC-FDMA without reference symbols but the equalizer was implemented in time domain making it unsuitable for channels with long impulse responses due to prohibitive computational complexity.
Examples included overcoming fear and fatalism regarding treatment, mediating the impact of family responses or the sometimes prohibitive cost of travel to treatment.
For frequency dependent visco-elastic sandwich structures, used in many industrial applications such as for vibration damping, the computation of the stochastic response can lead to a prohibitive computational cost.
The growth prohibitive properties of the AR or its response program can be exploited for developing novel prostate cancer therapeutic strategies.
Patients continued treatment until prohibitive toxicity, disease progression, achievement of maximal response or consent withdrawn.
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