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But the substance, the cocaine, is on the prohibited list.
The prohibited list is reviewed annually and is subject to change as new doping substances or methods are identified.
The IOC says a large number of asthma medications contain beta-2 agonists, which are on its prohibited list.
But it found that she was at "very significant fault" by failing to ascertain whether the drug was on the prohibited list.
But, added Wadler, who is chairman of the World Anti-Doping Agency's prohibited list and methods subcommittee, "there is no evidence for that at all".
"So they refer it to the Wada list committee, which does the research and concludes it should be on the prohibited list, and there it is".
The tribunal ruled that it had done so by publishing the prohibited list on its website and in its wallet cards.
TUEs can be issued to athletes who have an illness or condition which requires the use of medication that is on WADA's prohibited list.
An email landed at Sharapova Towers on 22 December advising her meldonium would be upgraded to the prohibited list on 1 January 2016.
I have always been careful to check my medication with doctors and medical support staff to ensure it does not contain any substance on the prohibited list.
"The fact that there's two different tests raising two separate questions creates a significant hurdle and starts to be problematic for the athlete," said Gary Wadler, the former chairman of WADA's prohibited list and methods committee.
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