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Although the many possible ways that a mutation can affect the observed binding affinity prohibited a straightforward interpretation the ΔΔ Go values in terms of the crystal structure of the complex, it is clear that the stability of the complex is the result of interactions that span the entire interface from the esterified amino acid to the T-loop 53 Å away.
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After a lot of constructive discussion the group decided that rather than beat around the bush with mixing and matching open-source licenses to discourage such behavior, we should create a straightforward clause that prohibits the behavior.
We show that such variable time lags are typical for complex nonlinear systems such as the climate, prohibiting straightforward use of correlation lags to infer causation.
The lower court sided with the couple, asserting that the case represented a straightforward instance of a business discriminating against gay people, which is prohibited under Colorado law.
The budget deal preserves a straightforward way to prevent a new fracking frenzy and surge in greenhouse pollution: President Obama can declare a national emergency and prohibit exports for a year -- and that prohibition can be renewed indefinitely.
A straightforward sandwich cheddar.
A straightforward hold.
A straightforward win.
That's a straightforward game.
Here's a straightforward question.
He was a straightforward man.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com