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As development proceeds, this primitive epithelium switches on a differentiation program leading to stratification: the ectodermal cytokeratins K8/K18-positive cells of the primitive epithelium are replaced by basal epidermal K5/K14-positive cells, and progressively, several layers of suprabasal differentiated cells appear offering an efficient resistance against environmental stress.
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A previously healthy teenage girl, who had immigrated to Oregon from Mexico as an infant, sought care in January 2000 for progressively severe headaches of several months duration.
The activity was chaired by Sweden and co-chaired by Italy and progressively involved several Member States and stakeholders in an EU-wide drafting group.
The activity was chaired by Sweden and co-chaired by Italy and progressively involved several Member States and stakeholders in an EU-wide drafting group (47 experts).
Note that RNAi-dependent DNA methylation in Arabidopsis thaliana was shown to occur progressively over several consecutive generations [62].
We show that early plant lineages acquired four characteristic architectures and progressively lost several primitive architectures.
We show that early plant lineages acquired four characteristic domain architectures and progressively lost several primitive domain architectures.
These neurological disorders may be established at the time of injury but it is not unusual for them to become progressively, with several days delay.
Two genetically distinct GBM IV classes are known: (i) secondary GBMs that develop progressively over several years from less malignant AS II or AS III, and (ii) primary GBMs that develop within few months without prior occurrences of lower grade astrocytomas [ 12, 13].
Whilst obligatory molecular determinants of doxepin-binding to HERG remain to be found, the fact that IHERG inhibition by doxepin developed progressively over several minutes following rapid external solution exchange is consistent with the drug crossing the cell membrane to reach its site of action.
We have implemented several progressively more efficient algorithms for the consistency checking problem for this class of temporal constraints: backtracking, backjumping, three variations of forward checking, and forward checking with backjumping.
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