Sentence examples for progressively occurring from inspiring English sources

On the other hand, these studies are modeling human neurodegenerative diseases with changes progressively occurring throughout many years or decades and in aging brains that typically can have multiple proteinopathies likely reducing the normal abilities to cope with protein misfolding.

Additionally, these data also suggest that quiescence associated with loss of Fucci-red positivity, according to Xouri et al. [ 23], is probably progressively occurring in cells located from 120 μm to the center of the spheroid.

It has been suggested that progressively occurring DNA methylation errors lead to diminished gene responsiveness to external stimuli and might thus contribute to the development of T2D (Gallou-Kabani and Junien, 2005).

In glioblastoma, for example, the genomic profile of primary cultures, assessed by array-CGH, resulted considerably different from that of parental tumors, with changes progressively occurring already after 2 weeks of culture, resulting in an inconsistent representation of tumor biology [ 22].

Beyond this temperature, the degradation progressively occurs and next major change in mass loss rate is additionally observed around 440 °C (Fig. 2f).

Then PP and the composites were subjected to dynamic packing injection molding, in which the melt was firstly injected into the mold then forced to move repeatedly in a chamber by two pistons that moved reversibly with the same frequency as the solidification progressively occurred from the mold wall to the molding core part.

To enhance the shear effect, so-called dynamic packing injection molding (DPIM), in which the melt is firstly injected into the mold and then forced to move repeatedly in a chamber by two pistons that move reversibly with the same frequency as the solidification progressively occurs from the mold wall to the molding core part, was used to obtain the molded bar.

However, we obtained opposite results in that irritating symptoms progressively occurred with advanced gestational age, in accordance with previous studies [ 7, 14].

In addition, global DNA hypomethylation is thought to constitute an early event in some cancers and can progressively occur and accumulate during aging (Wilson et al. 2007).

The best studied example of the importance of deamidation in protein function and lifetime is in the eye lens crystallins, which are long-lived proteins whose deamidation progressively occurs during life, resulting in aggregation and cataract formation [ 106].

Since a clear change of primary study design has progressively occurred along with incorporation in everyday practice of new evidence generated by research, we evaluated the impact of publication date on the overall effect of prone ventilation by a cumulative meta-analysis.