As shown in Figure 1B, the level of apoptosis was progressively elevated with increased doses of radiation.
Pulmonary arterial hypertension (PAH) is a fatal disease characterized by progressively elevated pulmonary vascular resistance, which results from vasoconstriction, vascular remodeling and in situ thrombosis.
Whereas, serum creatinine levels were progressively elevated, and she required hemodialysis in 15 months since the renal biopsy.
Malondialdehyde content was progressively elevated with the severity of stress, from CA, CCA to CS. Proline content exhibited different variation patterns.
The expression of Src also progressively elevated in HBV infected liver tissues → cirrhosis liver tissues → HBV-related HCC tissues (Additional file 1).
Consistently, both circulating levels of FGF21 and its hepatic mRNA expression were progressively elevated in apoE−/− mice with spontaneous development of hypercholesterolemia and atherosclerosis.
These results suggest that markers of inflammation are progressively elevated as kidney function declines, even in subjects without chronic kidney disease.
One key role is secretion of proteases that degrade extracellular matrix proteins and cause the follicle wall to weaken and eventually to rupture under progressively elevated follicular edema.
Although plasma total [Trp] is progressively elevated in these hepatic conditions, because of impaired degradation by TDO, the percentage free was still elevated from 22% in controls to 55% and 95% respectively (reflecting increases of 150%–332%).
Following thyroxine treatment, TSH levels suppress readily with elevation of FT3 to supraphysiologic levels; serum SHBG may rise further from high-normal baseline levels [13] and biochemical markers of bone turnover became progressively elevated in one case [16].
In patients with heart failure, plasma levels of ANP and BNP are progressively elevated in relation to the severity of the disease, so they have been widely used as markers of heart failure [ 4, 6, 11].
