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Herein, we describe the structures of three generations of single-chain pMHC progressively designed for the optimal presentation of covalently associated epitopes.
Systematic interventions are being planned and progressively designed on most buildings of the Arsenale of Venice, the Venetian republic's shipyard, a very large complex of docks and sheds of peculiar construction characteristics.
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In this approach we assist untrained users to progressively design the whole database structure of their applications.
By progressively designing mutations in CkPA04 we demonstrate that substitutions at the 137 and 193 positions (in addition to those in 226 and 228 positions) considerably alter the glycan receptor binding affinity.
Increasingly, ecosystem-based approaches to river rehabilitation are being adopted and fishways are progressively being designed for fish assemblages.
Alternatively, we propose a robust selection procedure designed to progressively skim the correspondences so that the computational cost is kept low at each stage.
Zeta potential was measured under conditions designed to progressively approach the environment under which flotation will be attempted: viz.
Two algorithms are designed for progressively selecting features, by firstly eliminating irrelevant features and then abandoning redundant features based on discrimination structure complementarity.
The leaching properties of a selection of aggregate materials are being examined in a testing programme designed to progressively simulate the real conditions within a road construction.
Cocoa butter (CB) systems were designed to progressively increase the number of heterogeneous nuclei within the CB matrix, and the crystallisation behaviour was studied at four temperatures (5 °C, 10 °C, 15 °C and 20 °C).
Additional reactions to give products corresponding to progressively smaller intervals were designed as necessary.
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