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However Echaniz-laguna et al., [ 23] and Grehl et al. [ 47] reported that normal mitochondrial function is progressively altered with the disease's progression secondarily.
Interestingly, the global subcellular distribution pattern of proteins phosphorylated on serine or tyrosine residues changed as MOSE cells progressed to a more malignant state, suggesting that signaling pathways were also becoming progressively altered.
In close-system control, on the other hand, the response is progressively altered by feedback so that all subsequent responses are adjusted to the initial response.
This agent was initially administered intravenously, but the mode of administration was progressively altered to subcutaneous without apparent increase in immune reaction.
Through significant public funding, the hydro-morphological regimes of mountain rivers in the European Alps have been progressively altered over the last century, with the aim to provide a safe dwelling space, to boost transport, mobility and to support economic growth.
In contrast, when oscillations were blocked by either LMB or CHX, intranuclear p65 mobility measured by line FRAP was progressively altered with time.
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In EMT, polarized epithelial (Epi) cells progressively alter their junctional and polarity complexes to acquire morphological and biochemical characteristics typical of mesenchymal (Mes) cells (Thiery et al, 2009).
These changes in the structure and composition of ECM progressively alter the biological and mechanical microenvironments that significantly modulate cellular activities as described later in this review.
While not measured in the current study, said humeral rotation might be expected to progressively alter SMA attitude, notwithstanding that surface tissue may not rotate precisely in concert with underlying bony structures.
E1 enzymes reorganize the three-dimensional arrangement of their domains to generate the active site environments for chemically distinct reactions and to progressively alter the affinities for their sequential macromolecular substrates.
In the root tips of Arabidopsis, cells divide regimentally to align in files; and within those files individual cells progressively alter their growth mechanisms, which at first support cell division, and then accelerated cell elongation, and finally cell differentiation and maturation, to form the root's functionally diverse tissues.
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