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In AD, tau becomes abnormally phosphorylated and forms inclusions throughout the brain, starting in the entorhinal cortex and progressively affecting additional brain regions as the disease progresses.
This exocytosis inhibition induces a flaccid paralysis progressively affecting all the muscles and generally engendering a respiratory distress.
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The form of polycystic (multiple-cyst) renal disease that allows survival into adult life is a familial condition, in which several members of the family have little trouble until middle life but then are progressively affected by kidney malfunction.
Since the failure of a local member detected by the proposed damage model at the material level progressively affects adjacent members, it can lead to eventual collapse of the entire system.
These results suggest that IRF3 and IRF7 can be activated by EBV but that IRF7 activity can be progressively affected after a prolonged stimulation with EBV.
These may include continuous social feedback between successive generations of artists and their audiences, and may progressively affect even basic aspects of motor control.
The long injection times and the regeneration procedures used between two binding assays progressively affect the mRNA integrity during the experiments [28].
Alström Syndrome [ALMS (MIM #203800)] is a rare, autosomal recessive monogenic disease characterized by a wide spectrum of clinical manifestations involving multiple organs, including blindness, severe insulin resistance, type 2 diabetes, obesity and cardiomyopathy that progressively affects multiple organ systems [1].
However, symptoms progressively affect certain behaviors driven by a particular brain circuitry.
Osmotic stress will increase these times and progressively affect biological reactions that rely on fast macromolecular diffusion.
As DNFB concentrations were increased, flagellar wave attenuation was gradually and progressively affected towards the more proximal regions and the mid-piece (Tombes et al. 1987).
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CEO of Professional Science Editing for Scientists @ prosciediting.com