Sentence examples for progressive turnover from inspiring English sources

Additionally, bone marrow-born LCs exhibited higher proliferative activity and also proliferated more potently in situ within the epidermis when compared to host-derived LCs, which suggests a progressive turnover of the resident LC compartment by bone marrow-derived LCs in psoriasis-like disease.

BAG3 was polyubiquitinated in MDA435 cells in the absence of stress, consistent with proteasome involvement in basal BAG3 turnover; progressive ubiquitination and subsequent BAG3 loss was observed with STS.

There was no progressive reduction of bone turnover markers with repeated annual dosing.

This could contribute to the absence of osteophyte formation, as well as to the increased subchondral bone turnover in rapidly progressive hip and knee OA [ 25, 26].

However, the disease course in mice was more slowly progressive than humans, suggesting substrate turnover differences between mice and humans as has been observed in Gaucher disease point mutation models in mice (38).

Using tracer methodologies, Normand-Lauzière et al. (10) also found a progressive increase in postprandial plasma FFA turnover from normal glucose tolerance to prediabetes and to type 2 diabetes.

Results demonstrated that from 1987 to 1999 the species diversity increased and the species turnover prevailed over nestedness, due to the progressive niche occupation by new species.

Protein turnover decreases with age, resulting in a progressive accumulation of damaged proteins and propagation of the aging phenotype (Stadtman, 1988, 1992).

Catalyst operation at high turnover frequency (TOF) was observed to cause a progressive change of Lewis acidity characteristics with time for both Ir and Ru cations thus influencing their ability to promote water oxidation.

Indeed, the progressive accumulation of polyubiquitinated protein conjugates, indicating a failure of proteasomal turnover, is a consistent feature of many neurodegenerative diseases [ 44], including ALS [ 1].

Altered bone turnover might be a diagnostic or therapeutic target in patients with progressive OA [ 16].