Exact(2)
The Etruscan world had been reduced to a circumscribed, regional sphere, secluded in its traditional values; this situation determined its progressive passage into the political system of Rome.
One can follow the progressive passage between the different polarons organizations displayed in function of the polarization potential: polaron lattice, then bipolaronic species are successively formed in the conductive range, and the passage from one to another form corresponds to the maximum of conductivity.
Similar(58)
Here we monitor the progressive loss of robustness in an in vitro model of the early stages of transformation that comprises normal keratinocytes and progressive passages of HPV16 immortalized cells.
The gene expression profile of tendon fibroblasts in monolayer culture has recently been shown to alter with progressive passaging [ 45].
We have also observed that MBP-1 knocked down HFFs displayed a flattend cellular morphology with progressive cell passage.
On the other hand, the expression of other markers on AT-MSCs, such as CD73, CD90, and CD166, increases during progressive stages of passage [ 122].
Lymphosarcoma causes thickening of the abomasal wall, which leads to progressive impairment of passage of ingesta, ulcers, haemorrhage, melena, anaemia and occasionally abomasal reflux and hypochloraemic alkalosis [ 2].
The relationship between cell size, morphology and senescence is well known and we have evidenced progressive accumulation with passage of larger and complex cells (estimated by forward and side scatter, respectively); in contrast, all hTERT-MSC cultures maintained a more homogeneous size and complexity throughout the culture.
The second group of differences corresponded to progressive changes along passages that were consistent with a selection process.
We suggest that this difference in growth rate is due to a progressive accumulation of passage-associated endogenous DNA damage at low oxygen culture conditions (3% O2).
Although the orthoxenograft generated from the S462 cell line reproduced the histological patterns of the NF1-associated orthoxenografts, genomic analysis showed progressive changes along passages consistent with a cellular and genetic selection process of the high heterogeneity present in in vitro cell cultures; a process that was not observed in the engraftment of primary tumors.
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