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Even at that time, when the writings of Gregor Mendel on genetics were lying unnoticed, Weismann saw that, since the hereditary substances from the two parents become mixed together in the fertilized egg, there would be a progressive increase in the amount of hereditary substances unless at some stage there was a compensating reduction.
LDTg lesions also blunted the effects of nicotine: control rats showed an initial locomotor depression after nicotine, but on repeated testing showed a progressive increase in the amount of locomotion in response to drug challenge.
In general, there was a progressive increase in the amount of neutralization after each successive DNA vaccination (data not shown) with maximal response at 1 week after the 3rd DNA immunization, with highest and most consistent levels in the trivalent vaccine group delivered with the Agro-Jet® device.
We observed, in SF, a progressive increase in the amount of IL-13, a cytokine usually described in allergic reactions and pulmonary fibrosis [ 70].
A progressive increase in the amount of p62 was observed in obese patients with steatosis and in obese patients with NASH compared to control patients.
As shown in Figure 2b, a progressive increase in the amount of EBC H2O2 was recorded as the cooling temperature decreased, with significant differences between -10 and +5°C and between -10 and 0°C (p < 0.01).
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Progressive increases in the amount of transfected p21WAF1/CIP1 cDNA resulted in a progressive inhibition of PLC/PRF/5 cell proliferation until maximum inhibition was obtained at 2 μg of the p21WAF1/CIP1 cDNA.
Specific feature of this process compared to the conventional EC' mechanism is the progressive increase in the overall amount of the components of the redox couple owing to consumed bromate.
As cells become motile, there is an increase in the amount of fibronectin basally, as well as a progressive increase in the levels of F-actin apically.
Following GTN infusion, there is a progressive increase in the intensity of the reflex EMG response.
In some cases, migraine patients experience a progressive increase in the frequency of the attacks, leading to headache chronification.
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