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The disease is associated with a variety of symptoms and functional deficits that result in a range of progressive impairments and handicap.
Flies overexpressing tau also exhibit progressive impairments of both motor and learning behaviors.
Clinically, AD is characterized by progressive impairments of memory, judgment, decision making, orientation to physical surroundings, and language.
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by polyarthritis and erosive synovitis and is associated with progressive impairments and activity limitations [ 1, 2].
AD is defined by progressive impairments in memory and cognition and by the presence of extracellular neuritic plaques (A β) and intracellular neurofibrillary tangles (tau protein) [ 5, 32].
Normal aging is accompanied by progressive impairments of the cardiovascular and circulation systems 8 characterized by adaptational difficulties in stressful situations (financial years, care), extremes for subjects with dementia.
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181 AD is a progressive neurodegenerative disease that involves a variety of symptoms such as progressive impairment of cognitive function, and impaired orientation and attention.
AD is a slowly progressive neurodegenerative disorder, with insidious onset and progressive impairment of general cognitive symptoms, such as impaired episodic memory, judgment, decision-making, and orientation [ 1, 2].
The progression of Duchenne muscular dystrophy (DMD) is characterized by a progressive impairment of muscle function leading to death due to cardio-pulmonary failure in the late teens or early twenties [1], [2], [3].
Dementia is an umbrella term describing a progressive impairment of the brain's higher mental functions.
In early and middle adult life the usual cause for progressive impairment of hearing is otosclerosis.
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