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As expected, because of the progressive differentiation, the control ESCs are capable of differentiating into various germ layer derivatives such as cardiac and neuronal cells.
The weak GFP expression seen in a low percentage of differentiating hES cells increased during the differentiation protocol, confirming the progressive differentiation of endoderm cells into hepatic cells.
An emerging challenge for understanding the Earth system is to determine the relative roles of early planetary processes versus progressive differentiation in shaping the Earth's chemical architecture.
(3) The insular cortex has passed through a spectacular progressive differentiation during hominoid evolution, but the assumption of Craig (2009) that the human anterior insula has no homologue in the rhesus monkey is untenable.
Moreover, the increased number of Gfap-positive cells and increased Gfap mRNA level after the induction of differentiation most likely support their progressive differentiation into a glial cell lineage, since Gfap is a marker that is upregulated in glial cells.
The Archean Anshan Complex in the northeastern part of the North China Craton is one of the few areas on Earth where rocks older than 3.8 Ga have been identified, and thus it provides a rare opportunity to determine the relative roles of primordial silicate differentiation versus progressive differentiation in shaping the Earth's chemical architecture.
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Pancreatic β cells develop by progressive instructive differentiation of pancreatic progenitors, which are derived as a result of the regionalized differentiation of the definitive endoderm (DE).
This pattern suggests progressive genetic differentiation from one population to the other suggesting an isolation-by-distance pattern.
In mouse OE, the progeny of GBCs undergo progressive terminal differentiation, from immature ORN expressing doublecortin and GAP 43 to mature ORN expressing OMP.
This progressive breed differentiation was accelerated by introduction of breed standards, which accumulated specific phenotypes that visibly distinguished particular breeds.
At this time, RHE is histologically similar to the human epidermis with respect to organized keratinocyte layers and progressive cellular differentiation.
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