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The steep increases of systolic blood pressure in the progressive clusters, coinciding with the time at which retinopathy progressed, suggest that progression of DR is influenced to a large extent by blood pressure and diabetes duration.
These patients showed lower risk factor levels of diabetic duration, HbA1c, FPG, and systolic blood pressure compared with patients in the two other small clusters of diabetic patients who showed progression of DR. Patients in these two progressive clusters are at high risk of persistent PDR and are therefore in need of strict and regular screening.
No progressive "clusters" could be found in visual field series of 14 eyes (34%, 81 visual field examinations).
Most of the progressive test locations and events were situated inside the operator-defined ROI and were concentrated in the progressive clusters.
Steep increases in systolic blood pressure in these progressive clusters were observed, which seemed to coincide with the point in time at which progression of DR occurred.
The remaining fraction represented both progressive (clusters 4, 5, 7, 8, and 11) and intermittent (clusters 1, 9 and 12) effects.
Similar(46)
Of the 30 eyes that did not meet our progression criterion, a progressive "cluster" was found in 16 eyes (53%) whose presence was not confirmed in subsequent examinations.
This progressive clustering procedure links sequences into progressively higher taxonomic groups (fig. 2 A ) and provides a comprehensive picture of the contents, diversity and relationships within the community.
Type-2 diabetes mellitus is a progressive cluster of metabolic disorders, representing a global public health burden affecting more than 366 million people worldwide.
Mixed cells exhibited progressive clustering of red CHO- α5β1(M) cells within a field of green CHO-P3 cells.
The algorithm is based on the idea of progressive cluster growth.
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