Sentence examples for progressive breakdown from inspiring English sources

The advent of Christianity, urbanization, and industrialization have resulted in a progressive breakdown of the Sotho's traditional culture patterns.

In the case of Huntington's disease, which causes a progressive breakdown of nerve cells in the brain, the technology could protect all children in the family, who would otherwise face a 50/50 chance of inheriting the disease.

It is easy to see the marginalisation of Britain in the EU, a progressive breakdown of relations and, ultimately perhaps, Britain's departure (see Bagehot).But equally, there could be a reconciliation.

Forming is to be perceived as a two-stage process consisting of oxygen vacancy filament nucleation (percolation) and subsequent filamentary growth (wear-out), corresponding to the soft (SBD) and progressive breakdown (PBD) regimes in oxide reliability.

If unchecked, the progressive breakdown in the mud-bank and associated mangrove system that has led to progradation of the coastal plain of Guyana over the last 5000 years will result in large-scale coastal erosion that can only be countered by further engineering structures at prohibitive costs.

AMD is characterized by the progressive breakdown of the macula (the central region of the retina), resulting in the loss of central vision including visual acuity.

It is also not possible to determine, with accuracy, which sites are undergoing progressive tissue breakdown.

At Stage 2 the parasites have invaded the central nervous system including the brain, and progressive neurological breakdown, including psychiatric disorders, depression and altered sleep wake patterns, ensues.

An understanding of the relationship between SLRP metabolism and progressive cartilage breakdown in OA may provide both novel diagnostic markers of disease and therapeutic targets for the treatment of this disorder.

11 Repetitive loading of the injured articular cartilage during sports activity leads to cellular degeneration, accumulation of catabolic enzymes and cytokines, disruption of collagen ultrastructure and progressive macroscopic breakdown of the articular surface.

It is evident that a phenotypic shift in the mature articular chondrocyte to a cell type that displays many characteristics typical of hypertrophic cells in the lower zones of the growth plate is a typical feature of OA and is associated with the progressive cartilage breakdown observed (reviewed in [ 2]).