Sentence examples for progressive abnormalities from inspiring English sources

To evaluate whether impaired fasting glucose (IFG) or the combination of IFG and impaired glucose tolerance (IGT) is associated with progressive abnormalities of cardiac geometry and function.

In conjunction with exploring the progressive abnormalities in iron homeostasis in AD, we also investigated age-associated changes in the expression of iron-handling proteins in the well-characterised APP transgenic (APP-tg) mouse (APP/PS1-tg2576) model [ 51- 54].

Even though evidence for the prevalence of SCI in adults is limited [ 40, 42], 50% of adult patients with SCD with normal baseline neurologic examination and no history of stroke or transient neurologic events had SCI, and 25% had progressive abnormalities on magnetic resonance imaging (MRI) during a 3.7-year follow-up [ 43].

Cerebral palsy was defined as a non-progressive abnormality of movement and posture, with increased tone and stretch reflexes in one or more extremities [ 17].

Ercc1 knockout mice (Ercc1 -/- ) are runted and suffer from severe progressive neurological abnormalities, kyphosis, and hepatic as well as renal nuclear abnormalities.

Destructive spondyloarthropathy is characterised by rapidly progressive radiographic abnormalities, including the loss of intervertebral disc space, erosion of the subchondral bone in the adjacent vertebral bodies and new bone formation (Fig. 7).

Classically, cancer has been viewed as a set of diseases that are driven by progressive genetic abnormalities that include mutations in tumour-suppressor genes and oncogenes, and chromosomal aberrations.

It is also known that progressive mitochondrial abnormalities and apoptotic cell death occur in the hearts of R120G TG mice.

Additionally, progressive gait abnormalities, ataxia, hindlimb clasping and a progressive decline in the forced motor function as measured by the rotarod test occur over time [10], [11].

Taken together, our observations demonstrate that reduced ena levels cause neuronal dysfunction in specific areas of the adult brain, leading to progressive behavioral abnormalities and neuronal death.

We have demonstrated that progressive mitochondrial abnormalities and apoptotic cell death occur in the hearts of R120G TG mice in previous studies [8], [9].