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Therefore, improvement rather than slowing of progression was required for most outcomes to demonstrate efficacy.
Continued evidence of disease progression was required after anti-androgen withdrawal.
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New methods for identifying bladder cancer (BCa) progression are required.
Further investigations of the roles and mechanistic pathways of CD44 in tumor initiation and progression are required to validate its role in CSC maintenance and regulation, and provide further insight on its usefulness as a specific therapeutic target.
Further investigations into LINE-1 methylation and cancer progression are required to test this concept.
Imaging-based evaluations for progression were required at each visit for the chest, abdomen and pelvis.
Studies that examine how individual variants and their associated phenotypes affect prostate cancer presentation and progression are required.
A better understanding of the cellular and molecular events that underlie AVD progression is required to develop novel approaches to treatment.
We aimed to determine the extent to which cell-cycle progression is required for either the specification of the presumptive cardiac field or for differentiation of Xenopus cardiomyocytes.
Therefore, new approaches to address the mechanisms of HCC progression are required to develop effective prognostic techniques and to discover new therapeutic targets.
It is well established that well-regulated tissue remodeling during both physiological and pathophysiological processes, including embryogenesis, wound healing and cancer progression, are required to maintain cellular homeostasis (Johnsen et al., 1998).
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CEO of Professional Science Editing for Scientists @ prosciediting.com