Sentence examples for progression to phase from inspiring English sources
The potency testing is critical for the development of hPSC-based cell therapy products and is needed before progression to phase III clinical trials.
The safety and pharmacokinetic profile of OZ439 merits progression to phase 2a proof of concept studies in the target population of acute uncomplicated malaria.
If the number of sites on an APC that can form stable interactions with CD8+ T cells are limiting, perhaps CD8+ T cells compete for progression to phase two.
It can potentially validate inhibition of the molecular target of the drug; identify subgroups of patients who may not be candidates for the drug in question (triple negative tumours for EGFR inhibitors, to follow the example above); and provide knowledge to assist in a 'go versus no-go' decision regarding progression to phase II or III drug development.
"We're very pleased with Boeing's progress on the XS-1 through Phase 1 of the program and look forward to continuing our close collaboration in this newly funded progression to Phases 2 and 3 fabrication and flight," said DARPA program manager Jess Sponable in a news release.
Upon phosphorylation by cyclin D/CDK4/6 complexes, pRb becomes inactivated and allows progression to S-phase.
Hence suppression of ER signaling leads to inhibition of CDK activity and the maintenance of Rb in a phosphorylated and active state inhibiting progression to S-phase.
According to the IRIS clinical trial, estimated rates of freedom from progression to accelerated phase and blast phase or overall survival at six years were 61%and76%6% respectively.
These findings support that sublethal DSBs cause differentiated neurons to re-enter G1 phase, but without subsequent progression to S phase.
As shown in Fig. 2b, the vast majority of the starved cells existed at the propidium-iodide-low G0/G1 phase and showed little progression to S phase.
Flow cytometric analysis showed that HGF caused an increase in the area of S phase with a reciprocal decrease in that of G1 phase, suggesting that HGF promoted cell cycle progression to S phase.
