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Late CKD diagnosis results in the ineffective treatment to delay progression to end stage.
Primary outcome was progression to end stage kidney failure or kidney function (eGFR) decline ≥ 50% of baseline.
Progression to end stage renal impairment may develop within 10-15 yealthoughhough may be slowed by early introduction of allopurinol [ 5].
Early management of high risk CKD by a nephrologist has been shown to slow progression to End Stage Renal Disease (ESRD) [ 7- 13].
Complications of CKD include progression to end stage renal disease and need for costly dialysis or renal transplantation, bone disease and premature cardiovascular disease (CVD) morbidity and mortality.
Patients with resistant focal segmental glomerulosclerosis (FSGS) who are unresponsive to corticosteroids and other immunosuppressive agents are at very high risk of progression to end stage kidney disease.
Similar(43)
How cardiovascular (CV) events affect progression to end-stage renal disease (ESRD), particularly in the setting of type 2 diabetes, remains uncertain.
Steroid-resistant nephrotic syndrome (SRNS) affects both children and adults and has a high rate of progression to end-stage renal disease.
Patients with primary focal segmental glomerulosclerosis (FSGS) resistant to current treatment regimens are at high risk of progression to end-stage kidney disease.
However, a subset of patients has a short duration of symptoms with rapid progression to end-stage disease.
Up to a fifth of FSGS affected patients have a high risk for progression to end-stage renal disease [2].
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