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Instead of inhibiting cancer progression, this function seems to act in combination with a pro-angiogenic activity of this transcription factor to favour the establishment of appropriately fed, well oxygenized, strong and thus potentially aggressive tumours.
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For instance, EPH receptors and their ligands can regulate stem/progenitor cell proliferation in adult tissues as well as tumor progression; this is a relevant function of EPH receptors in the context of oncology [47].
In practice, this added level of validation necessitates the development of an OAG disease progression probability function, since knowledge about future visits is not available to clinicians when identifying whether a patient has progressed.
They are involved in parasite containment, tumor progression, and function to dampen immune responses [12].
EV-mediated processes shape phenomena as diverse as cancer progression, immune function, and wound healing.
A point of discussion could be our choice of outcome measure inclusion, i.e., including and comparing pain progression, physical function decline and knee joint surgery.
We highlight recent findings on MCPH proteins with regard to their role in cell cycle progression, centrosome function, and early brain development.
Whether IL-17A and IL-17F expression is related to longitudinal clinical outcomes, such as disease progression, lung function decline, and exacerbations, requires further examination.
Overall, our clinical results imply that IGFBP-rP1, as a suppressor of CRC progression, may function to oppose the EMT program.
The rotarod apparatus (AccuScan Instruments, Columbus, Ohio) was used to monitor disease progression, motor function and balance of CLN6 mice and control littermates (n = 22-24 per genotyper.
The molecular mechanism of L2H17-mediated inhibition of tumor promotion and progression were function through inactivated NF-κB and Akt signaling pathways.
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