Sentence examples for progression the role from inspiring English sources

While TβRIII expression is lost during breast cancer progression, the role of TβRIII in regulating BMP signaling in normal mammary epithelium and breast cancer cells has not been examined.

Even though c-MYC was shown to strongly cooperate with K-Ras in lung tumor progression, the role of c-MYC in this process could not be evaluated as neither model gave rise to metastasis.

While the tumour microenvironment is known to contribute to tumour progression, the role of carcinoma-associated fibroblasts (CAFs) remains controversial and their origin unclear.

Although matrix metalloproteinases (MMPs) are implicated in tumourigenesis and cancer progression, the role of MMP-13 in melanoma cell metastases is poorly understood.

The generated LNCaP/Luc model has potential as a new tool to evaluate disease progression, the role of AR and PHB in this process, and to test new therapies for prostate cancer treatment.

To generate a novel mammalian model of ACDase deficiency to allow us to better study FD progression, the role of lysosomal ceramide in vivo, and evaluate experimental therapies, we introduced a single nucleotide mutation into the murine Asah1 coding sequence via genomic recombination ("knock-in").

To better understand their functions in the progression, especially the role of the sub-network in the progression, we need to find out which function is significant comparing to the whole human biological network.

An important feature of metastatic progression is the role had by the tumour microenvironment and the promotion of tumour growth, invasion and angiogenesis by the cancer-associated stroma.

An increasing body of evidence indicates that miRNAs have a critical role in carcinogenesis and cancer progression; however, the role of miRNAs in the tumorigenesis of adencarcinoma of gastric esophageal junction (AGEJ) remains largely unclear.

This study, to our knowledge, represents the first analysis of the expression of TLR7/8 on monocytes during HIV disease progression and the role of TLR7/8 triggering in monocytes on viral replication.

The majority of hybridization array studies using the cuprizone model have focused on demyelination progression and the role of inflammatory components (Arnett et al., 2003; Jurevics et al., 2002; Morell et al., 1998).