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Patients were deemed to have progressed if their progression status could not be determined.
Patients alive at week 8 were included in the PRO and OS analyses and categorised by their week 8 progression status as follows: no progressive disease (no PD; best response of at least stable disease) vs progressive disease (PD).
We advocate the creation of progression endpoints that utilize all available progression data rather than early fixed timepoint analyses and show that little is to be gained by assessing progression status any more frequently than would be required in routine clinical practice.
In the context of a randomised blinded trial, the exact choice of end-point is less critical, although we favour end-points such as the change in tumour size or progression status at a fixed early time point (i.e. 8 12 weeks after randomisation).
Additionally, a lack of visibility into the progression, status and results of QA testing has made it difficult for DevOps teams to determine if the code they built is truly aligned with the business and customer requirements.
These three risk tiers were defined using only progression status at 2 years and 4 years after analyzed specimens were obtained.
In the present study, we evaluated whether prior disease progression status (LTNP) or duration of pre-ART immunosuppression predicted an altered rate of recovery following ART initiation in a cohort where ART was scarcely available from 1985 2004.
We hypothesized that prior HIV disease progression status and/or duration of pre-ART immunosuppression (defined as the length of time with CD4≤200 prior to ART initiation) would constitute additional independent predictors of poor immune reconstitution on ART, in addition to the nadir CD4+ T cell count, and might need to be considered by ART providers.
In 77 patients (9 %), progression status was unknown.
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Furthermore, HCV coinfection was correlated with long-term non-progression status [24].
I actually enjoyed being on the SLT most of the time, but some dramatic life events taught me that data, progression and status are not everything.
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