Sentence examples for progression significant from inspiring English sources

Although everolimus can slow tumor progression, significant tumor reduction is rarely obtained.

Treatment was pursued unless disease progression, significant toxicity or the patient's voluntary withdrawal occurred.

During cancer progression, significant changes can be observed in the structural and mechanical properties of the ECM components.

Indeed, the present data show that in the absence of radiographic scoring the change in DXR-BMD was an independent predictor of radiographic progression, significant at two years, but not at five and eight years.

Additionally, with disease progression significant extrapulmonary systemic effects can be observed in patients, especially in patients with moderate to severe airway obstruction: skeletal muscle dysfunction and weakness, nutritional abnormalities and weight loss [ 1, 3].

Treatment was administered until disease progression, significant intercurrent illness, unacceptable adverse event(s), withdrawal of consent, noncompliance, need to stop therapy for toxicity for more than 28 days, or at the discretion of the treating physician.

Cancer biomarkers and genetic variation in both CTCs and DTCs may evolve during disease progression, and significant molecular discordance with important therapeutic implications may develop between the primary tumor and disseminated cells [83].

Since the degree of proteinuria correlates with tubular interstitial fibrosis the early treatment of proteinuria and prevention of progression to significant proteinuria levels is an important step to delay disease progression.

64 Cost savings per patient before and after disease progression were significant for anastrozole over tamoxifen (P<0.01), an important consideration when choosing ABC treatment.

The model demonstrates gradual progression and significant stromal infiltration.

Both diseases exhibit monotonic disease progression and significant patient heterogeneity.