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Control mechanisms: The mechanisms decision makers use to review data, to make and document decisions and to control progress of a study, namely Study Progression Rules and Toxicity Rules.
Changes to the pay progression rules will penalise doctors who are taking time out of their regular training to contribute to research in medicine, carry out humanitarian work or have a family.
The progression rules for the cognitive training were made by a virtual coach, who chose, for each exercise, the difficulty level: if the exercise was successful (100%%), the participant passed to the next level, if the score was between 70 and 99%%, the participant remained at the same level, and if the score was below 70%% three times in a row, the participant went down to the lower level).
To maintain participant engagement and adherence, new exercises will be introduced based on progression rules.
An overview of dose adjustment and disease progression rules is provided in Table 1.
The finding that some proteins had increased expression levels with disease progression rules out the possibility that the protein changes observed were simply occurring due to a loss of total neuronal protein content.
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Three difficulty levels were available for each training situation and a progression rule was also defined.2 Each participant began the simulated drive at the easiest level.
Several other plant and animal groups have demonstrated divergence patterns among species that are consistent with colonization from older to younger islands, often referred to as the "progression rule" [17], but this was the first study to find such a pattern within a species.
Evidence for the progression rule in Clermontia is clear.
This creates a progression rule pattern [ 1, 46].
Arbogast et al. [ 27] showed that the mitochondrial DNA (mtDNA) phylogeny of mockingbirds largely follows the progression rule.
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