Sentence examples for progression regulation from inspiring English sources

These include a role in cell cycle progression, regulation of transcription and cell surface signaling (reviewed in [ 20- 22]).

Finally, group G (remaining Rickettsiales), composed mainly of pathogens, has few of the factors involved in Caulobacter cell cycle progression regulation.

The essential nuclear functions of PKM2 in tumorigenesis include transcription factor co-activator, histone kinase, G1/S progression regulation, and the Warburg effect.

ASH and NASH display similar pathological processes, such as steatosis, hepatic inflammation, liver fibrosis, cirrhosis and hepatocarcinogenesis. 3 To manage ASH and NASH progression, regulation of the inflammatory response may be beneficial.

Additionally, the activities associated with capsaicin-induced anti-cancer effects include the arrest of cell cycle progression, regulation of transcription factor expression, and suppression of growth signal transduction pathways.

In addition to CDKN1A, other genes detected as differentially expressed have been involved in cell cycle progression regulation at G1, such as CDKN2B, CCNE2, CLK2, GSK3B, PPP2R5C, E2F2, PPM1A, TFDP2, CCNA1, and DCD14A.

Thus RASSF1A may mediate its tumour suppressive effects by inducing growth arrest in the G1 and G2/M phases and regulating mitotic progression via regulation of the APC complex and accumulation of cyclins A, B and D1 [133,144,146,147].

In the present study, the effect of ABI3 expression on cell senescence, coupled with inhibition of cell cycle progression, up regulation of p21WAF1 and down regulation of E2F1 expression, occurred in cancer cells in which p53 function is disrupted [ 24].

Both DLK1 and MEG3 exert various functions relevant for cancer development and progression, including regulation of growth factors and Notch signaling by DLK1, and regulation of TP53, pRB1 and NOTCH activity by MEG3 [ 20– 20].

This talk will highlight in silico approaches towards next-generation drug discovery along with relevant resources and datasets that are/can be integrated to achieve a 'systems biology' picture of disease progression and regulation.

Matrix metalloproteinases (MMPs) are attractive biological targets that play a key role in many physiopathological processes such as degradation of extracellular matrix proteins, release and cleavage of cell-surface receptors, tumour progression, homeostatic regulation and innate immunity.