Sentence examples for progression producing from inspiring English sources

These data demonstrate that Slbp15 mutant cells have a cell cycle defect, and are consistent with a model where impaired chromatin assembly capability impedes S-phase progression, producing DNA damage, genomic instability, and delayed mitosis.

Substitution of tamoxifen by anastrozole on progression produced no significant change in LH levels.

Substitution of tamoxifen by anastrozole on progression produced a further 18% fall from 4.2 to 3.4 pmol l−1 (P<0.02).

In general, any disruption of replication progression produces an accumulation of ssDNA believed to be mainly on the lagging strand (Sogo et al. 2002).

Targeted inhibition of TGFβ signaling may be an effective approach towards retarding AMD progression and producing RPE cells in quantity for research and cell-based therapies.

Inflammatory cell infiltrates, particularly macrophages, may contribute to tumour progression by producing angiogenic factors (Gruber et al, 1995; Jenkins et al, 1995).

The concentration of sHA is thought to reflect the extent of synovitis, which is present at the onset of OA and accelerates disease progression by producing proteases and cytokines [ 16– 16].

M1 macrophages mediate tumor suppression through type I cytokine production and tumor antigen acquisition and presentation [ 142, 144], whereas M2 macrophages promote tumor progression by producing type II cytokines [ 145].

Inflammatory cells are well established to promote tumor progression by producing such factors as cytokines, chemokines, and matrix metalloproteases that can enhance the malignant characteristics of neoplastic cells as well as remodeling the tumor microenvironment to support tumor growth and progression.

In contrast, postmitotic multiciliated cells (MCCs) uncouple centriole assembly from cell cycle progression and produce hundreds of centrioles in the absence of DNA replication to serve as basal bodies for motile cilia.

Mutant BRCA1 inhibited cell cycle progression and produced increased survival in cells with double-strand breaks.