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Similarly, patients on continuous treatment were assumed to require monitoring consultations only once every 3 months, on the grounds that ophthalmologists would want information about disease progression periodically, irrespective of whether treatment decisions are required.
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Review the progress periodically.
Patient 3, while on nilotinib monotherapy for 847 days, experienced meningeal progression and periodically received additional intrathecal chemotherapy and rituximab from thereon until systemic progression with detection of T315I and F317L mutation.
Thus, it will be very cost-effective for long-time administration since the frequency of monitoring the disease progression and therapeutic response periodically will be greatly reduced.
Two E3 complexes, APC and Skp1/Cullin/F-box (SCF), are known to control cell cycle progression [ 39] by regulating the periodically selective degradation of cyclins and other cell cycle regulators such as CDC6 [ 40], CDT1a [ 41], E2Fc [ 42], and the CDK inhibitor ICK2/KRP2[ 43- 45].
Subsequently, the photoperiod and temperature conditions were adjusted periodically to approximate the progression of fall, winter, and spring conditions in North Carolina (Fig. 2).
Review the conversation periodically to assess its progression and add additional comments.
One hundred and eleven years later, world record collection shows the progression of human performance as elite athletes periodically pushed back the frontiers of "ultra-physiology".
Periodically evaluate your progress.
For example, CLB6 promotes progression of cells into the S phase and expresses periodically throughout the cell cycle [ 16].
It is widely assumed that scoliosis should not be treated conservatively but instead periodically observed and, in case of considerable progression to the threshold values of the curvature angle, surgical intervention is suggested [ 8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com