Sentence examples for progression of transformation from inspiring English sources

This feature of the normal cells was lost in the progression of transformation.

This suggests that each category of SMC tumours arises as a distinct entity and that there is no progression of transformation in these tissues.

The early downregulation of MLH1 and a later incorporation of MSH2 defect indicate an important role of MMR in the initiation and progression of transformation.

Thus, by this approach we could satisfactorily meet the second objective of this project to unequivocally show, at least in one case, that AhR indeed contributes significantly to the progression of transformation of mammary epithelial cells.

Microvessel density and VEGF expression also increase in a linear manner with the progression of transformation in anal intraepithelial neoplasia, the precursor of anal SCC (Mullerat et al, 2003).

Based on the full-field strain measurements, the phase fractions during the nucleation and the progression of the transformation are obtained.

These data suggest that chronic colitis enhances the progression of early transformation events initiated by AOM, perhaps through establishing a microenvironment more supportive of cellular proliferation.

Promoter hypermethylation is a common inactivation mechanism in the development and progression of neoplastic transformation.

Unexpectedly, however, recent advances in genome-wide analysis revealed that the number of methylated genes declines markedly with the progression of malignant transformation of plasma cells [ 15, 16].

19– 22 The stabilization and overexpression of these oncoproteins have been implicated in the development and progression of cellular transformation.

Further in vivo studies using animal models of OSCC are needed to explore the functional role of IFN-stimulated M1 macrophages in the progression of malignant transformation.