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The majority (n = 14) of patients died either due to progressive disease or complications while suffering from progression of the underlying malignancy.
However, progression of arthritis in the lateral compartment could be simply caused by the natural progression of the underlying arthritic disease [24].
Based on a recent study, we demonstrate why mechanical dysfunction accompanying parenchymal diseases such as pulmonary fibrosis and emphysema can follow a very different course from the progression of the underlying microscopic pathophysiology itself, particularly in the early stages.
The remaining three patients discontinued the drug because of progression of the underlying cancer.
The importance of cumulative MB burden is double: first, it may produce further widespread damage over brain structures; and, second, it highlights the progression of the underlying SVD.
Underlying pulmonary diseases were inherent to our study population and the outcome could have been influenced by the progression of the underlying pulmonary condition rather than therapeutic failure.
Similar(20)
Chronically elevated BP is an important determinant for the development and progression of atherosclerosis, the underlying pathology for most cardiovascular events.
RHF has long been hypothesized as one of the main mechanisms of renal disease progression, irrespective of the underlying causes of CKD and the measures alleviating RHF, such as restriction of dietary protein and salt intake and anti-hypertensive therapy, especially the renin-angiotensin-aldosterone system blockers, have been recommended to patients with CKD [ 18].
One of the essential traits of cancer progression is the underlying high mutational capacity of tumor cells [ 7- 9], having as a consequence the rapid adaptive capacity of the disease.
NTI can be characterized by a variety of abnormal TFT patterns, which may evolve/change with progression or resolution of the underlying primary disorder (Fig. 2).
The progression from the underlying scientific study of Lipitor, expressly reporting no benefit for women, to Pfizer's advertising of the world's best selling drug while failing to disclose the absence of benefit for women raises grave concern about the FDA's regulation of drugs and drug company candor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com