The primary objective of the RAVE study is to determine the frequency of progression to the composite endpoint, death, dialysis and doubling of creatinine, in patients with ARVD and an indication for revascularization, randomized to medical therapy or renal revascularization over a minimum of 6 months.
The primary objective of the RAVE study is to determine the frequency of progression to the composite endpoint, death or dialysis or doubling of creatinine, in patients with ARVD stratified by the renal resistance index.
The progression of the ZnO-PVP composite structure from grains to nanofibers was observed, and ZnO-PVP nanofibers as thin as 29.9 ± 0.8 nm on average were successfully fabricated.
During the follow-up of 6.6 ± 1.2 years (median 7.6 years), 16.5% of the subjects noted the development or progression of diabetic retinopathy (composite retinal outcome), 5.4% of the subjects developed advanced diabetic retinopathy, 19.5% of subjects had progressive loss of renal function, 12.9% of subjects suffered from cardiovascular events, and 17.0% of subjects died.
Accordingly, one of the COCOMAT work packages involves the design of test panels with a focus on investigating the progression of composite damage mechanisms.
Despite the recent success of modeling progressive damage of open-hole fiber reinforced composites subjected to tension (OHT), it is still a challenging task to predict the strengths and the damage progression of open-hole composite laminates under compressive loading (OHC).
Also, the damage state can be evolved into the future enabling simulation of damage progression and prediction of remaining useful life of the composite material.
The aim of this numerical strategy is to investigate the global postbuckling behaviour as well as the local damage progression of composite structures using separated FE models with different levels of fidelity: (i) a relatively simple global model of the complete structure, and (ii) more complex local models of certain details that incorporate damage capabilities to simulate damage events.
Despite the rapid advances of numerical methods and theoretical models for progressive failure analysis of composites, it's still a challenge to predict the strength and damage progression of composite laminates under open-hole tension (OHT).
