Exact(3)
The 15.5 dpc embryonic mouse kidney contains subcompartments representing all progression of states during renal development [ 5].
That is, it is not clear that pathobio-logical progression of states seen to underlie toxic effects in test animals at high doses has a counterpart in humans who are not exposed or exposed only to much smaller amounts.
By definition, a node x i that is not impacted by damage to node x j will not change its state (for steady states) or usual progression of states (for limit cycles) as a direct result, i.e. f i x 1 t, …, x j − 1 t, 0, x j + 1 t, …, x n t = f i x 1 t, …, x j − 1 t, 1, x j + 1 t, …, x N t for all a k, k = 1,…, n.
Similar(57)
Furthermore, studies focused on biomechanics and the biophysical properties of cells are important in the understanding of the onset and progression of disease states, for example cancer at the cellular level.
Detecting biomarkers at pg/ml concentrations or below is, in many situations, critical for quantifying levels in healthy individuals as well as the changes that can occur in the progression of disease states.
Moreover, most animal experiments only focused on the progression of shock states during a very short time period rarely exceeding 24 hours.
The presence of such homologs for other genes in the Drosophila neuroblast cascade in subsets of RPCs during mouse retinal development suggests that a cascade similar to that in Drosophila might be playing a role in the progression of competence states in the murine retina as well.
The progression of these states generates a complex ramified structure that irregularly fills the surrounding environment (Fig. 2).
Impedance properties often change with changes in structure, composition, and metabolism, and can be indicative of the onset and progression of disease states.
However, strictly controlling cardiovascular risk factors is often difficult to obtain and the progression of pathological states has not been completely prevented with current pharmacological therapeutic options.
While modulation of channel opening can induce a rapid and reversible change in cell excitability, alterations in BK channel trafficking and localization could underlie long-lasting changes in cell activity, especially relevant to the development and progression of disease states.
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