In PRLR knockout studies on mice, the normal progression of hair replacement and follicle development have been observed [ 26].
We found differences in the progression of joint replacement procedures after the initial total hip arthroplasty regarding type of joint, age, and sex.
The Y chromosome scenario in Figure 2 describes the progression for replacement of the initial paternal gene pool of Austronesian-speaking migrants by locally acquired Melanesian genes.
The main outcomes of interest in the CanPREDDICT study include renal endpoints: progression of CKD to renal replacement therapy (RRT), CV events (both heart failure and ischemic events) and death.
This highlights the importance of bone shape and concurs with our conclusion that 3D knee shape and 2D hip shape are independently associated with structural progression of OA and total joint replacement.
Fifteen different definitions were used to define progression of cOA, including knee joint replacement, symptom severity on the Western Ontario and McMasters osteoarthritis index (WOMAC) scales for pain, function or stiffness and visual analogue scale (VAS) for pain.
Our objective is to identify characteristics that predict the rate of progression to renal replacement therapy (RRT) and evaluate how those characteristics predict mortality and a composite end point (RRT and mortality).
For example, among African Americans compared with Caucasians [ 46], we have reported a higher prevalence of specific radiographic features, such as superior joint space narrowing, previously found to be predictive of progression to hip replacement [ 47].
Benefits of early nephrology care for CKD are well-established: slowed progression of disease, better preparation for renal replacement therapy (RRT), greater likelihood of outpatient hemodialysis initiation, and reduced mortality [ 4- 6].
Møller et al (2003), in a study of 71 patients with carcinoid syndrome and 32 patients referred directly for valve replacement, demonstrated that progression of cardiac involvement, in 35% of patients, was associated with higher urinary 5-hydroxyindoleacetic acid (5-HIAA) levels and was more likely in patients who had received chemotherapy.
