Therefore, we investigated the efficacy of corneal cross-linking with riboflavin in halting the progression of keratoconus by conducting a placebo-controlled, randomized, blinded, multicentric clinical trial that included an independent control group.
To identify the outcome variables and statistical methods commonly used to investigate the effects of risk factors on progression of CKD, we conducted a literature review restricted to papers written in English language and published from January 2002 to October 1st, 2012.
To address whether specific transcription factors are involved in the regulation of genes associated with the progression of PAD, we conducted a transcription factor binding site enrichment study by analyzing cross-species conserved binding sites in promoter regions of genes differentially regulated during progression of PAD.
The distribution of i) patients according to cancer type, diagnosis by histopathology and progression of disease, ii) conducted staging procedures and iii) site of primary and distant sites of cancer for the patients with distant metastases are shown in details in additional files 1, 2 and 3: [see Additional file 1, 2 and 3].
An important strategy for unraveling the mechanisms of initiation and progression of cancer is to conduct analysis of complex genetic and molecular networks and study their behaviors under genetic and environment perturbations.
An important strategy for unraveling the mechanisms of initiation and progression of cancer is to conduct analysis of complex biological networks and study their behaviors under genetic and epigenetic perturbations.
For line II, detailed histological progression of liver tumors was conducted with the F2 generation.
Identification of groups of genes that behave similarly during progression of prostate cancer was conducted through K-means clustering of tags using the PoissonC algorithm [ 30].
This hypothesis is supported by positive findings in vivo on the progression of lesions in studies conducted in the experimental canine model of OA [ 64- 66].
We hypothesized that these truncated APC proteins may actually play a dominant (gain of function) role in the initiation and/or progression of CRC and have conducted experiments to test this idea.
This study of baseline predictors of progression of calcified atherosclerosis was conducted within a trial of glucose control, which has the potential to induce greater variation during the trial in certain risk factors in the intensively treated groups, thereby possibly lessening the association with CAC or AAC progression.
