Exact(16)
The results indicated that, among other factors, vitamin D deficiency can probably contribute to the progression of active disease in patients with SLE.
All the above results indicate that the DNA repair pathway not only exerts functions directly on the active DNA demethylation but also maintains the progression of active DNA demethylation and repairs the active DNA demethylation-induced DNA damages.
The specific immune responses or factors responsible for progression of active tuberculosis are not well characterized.
High variability of IGRA results during progression of active TB infection related to various phases of infection was obtained.
To test for an effect on the progression of active disease, we induced EAE with a primary immunization with p35 55 in CFA.
Patients with metastatic GCC developing first progression of active cancer despite initial cisplatin-containing chemotherapy almost all require salvage combination chemotherapy.
Similar(44)
Consistent with a negative role in cell cycle progression, expression of active MKK3/6 induces G1 arrest in the same cell line [ 10].
Treatment of latent tuberculosis infection (LTBI) can significantly reduce the risk of progression for active TB and of death among PLWHA [ 1, 3– 5].
Our interpretation of progression at the time of screening potentially includes both early and late progressors because of uncertainty of the timing of progression to active disease.
However, because persons co-infected with HIV and M. tuberculosis have the highest rates of progression to active disease, continued monitoring of co-infected patients is essential for control of TB.
Treatment of LTBI reduces the risk of progression to active TB, 3 which in the setting of HIV co-infection is more severe and associated with extrapulmonary disease 4 6 and reduces the risk of onward transmission and infection.
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