Sentence examples for progression of a cell from inspiring English sources

The progression of a cell through the cell cycle is promoted by cyclin dependent kinases (CDKs), which are positively regulated by cyclins and negatively regulated by CDK inhibitors [53],[53].

Cyclin levels are known to mirror the progression of a cell within the cell cycle.

The threshold for transition between the arrest and the progression of a cell cycle was represented by A H i, j.

Thus, an unequal stop of cell division might be realised through a faster acropetal progression of a cell division stop front in adaxial petals compared to abaxial petals.

In contrast, insertional mutagenesis using retroviruses and transposons is an effective approach for inducing the stepwise progression of a cell to malignancy, and for the identification of the causal genetic lesions, because the mutagen acts as a molecular 'tag' allowing its location in the genome to be easily determined.

These studies have determined that only a fraction of genetic alterations contributing to tumorigenesis may be inherited, while somatically acquired mutations can contribute decisively during the progression of a normal cell to a cancer cell.

Because the progression of a normal cell to a cancer cell involves numerous genetic mutations, targeting one or even several gene products may be ineffective.

In order to validate the efficacy of the combination regimen, apoptosis assay was conducted which determined the progression of a cancer cell from four different phases after the addition of the drug: living cell, early apoptotic cell, late apoptotic cell and necrotic cells.

From this point of view, DS MK cells would be the ideal control for the progression of a trisomic cell toward TMD and AMKL, however no gene expression profile dataset was available for this cell type.

These results suggest that there are two different types of tumor-suppressor genes: one is the gene whose inactivation is responsible for malignant transformation of a normal cell and the other is the gene whose inactivation is responsible for the progression of a tumor cell.

The progression of a normal cell towards a neoplastic state comprises a cascade of events that are responsible for inducing tumorigenesis [ 31].