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Fig. 2 illustrates the fellows' progression milestones.
Additional file 2: Figure S2 depicts the disease progression milestones for 20 simulated patients with recurrence based on the calibrated parameters.
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More rapid progression to prespecified milestones can be achieved by enriching the population with risk factors.
1 Contemporaneously, changes in surgical training were implemented with the aim of streamlining progression through training milestones and shortening the duration of training.
Figure 3 Decision flow chart of project milestone progression and scientist reassignment priority.
For example, if there are first-in-class drug candidates with an unproven MOA, or there are too many clinical candidates competing for development resources, then it may be necessary to review the milestone progression criteria and adjust them accordingly with an eye toward achieving clinical POC as soon as possible.
Clear job roles, definitions and routes to progression, coupled with objectives and milestones for them to strive for, are the key to keeping the modern workforce hungry for your collective success.
Moreover, utilizing established disease measures in canine models provide sensitive and specific milestones of disease progression and therapeutic response that parallels surrogate markers used in human patients.
For example, there are few cell surface antigens that can be used as milestones of lineage progression.
The ARCP/RITA assessments are there to monitor training progression against specific competencies and milestones and are not a direct measure of the quality of doctors.
Biological changes underlying malignant transformation are complex, but key events such as angiogenesis, induced in part by alterations in oxygen tension and growth factors, represent critical milestones in tumour progression, self-preservation and survival [ 2, 3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com