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Follow-up showed that patients with koilocytosis had a significantly lower likelihood of progression (log-rank=5.5, p=0.02).
In contrast to the pattern with sCD14, having above the median level of IL-6 in plasma was a significant predictor of faster disease progression (log-rank P = 0.023, HR 0.462, 95% CI = 0.238-0.900) (Figure 4H).
As shown in Figure 1, the Kaplan-Meier analysis revealed that patients with elevated pretreatment serum EPCA levels (greater than the median value of 15.20 ng/ml) had an increased probability of PSA progression (log-rank test, P<0.001).
Combining ANXA10 and p53 expression resulted in a highly significant prediction of progression (P<0.00001, log rank test; Figure 1C).
The identification of ≥2 CTCs predicted shorter progression-free (log rank P ≤ 0.001; hazard ratio 8.30, 95%% CI 2.61 26.37) and overall survival (log rank P = 0.0004; hazard ratio 7.19, 95%% CI 1.98 26.06) versus survival for patients with <2 CTCs.
Laporte et al. [52] used an extensive time-series of contrast-enhanced Landsat data to map the progression of logging roads in Central Africa.
Spectral fractions or spatial filtering of a monthly time-series of optical data can reveal the progression of logging roads, and combined to produce an annual synthesis of change.
Because scores were not normally distributed, the log-transformed progression rate (log rate +1) was used.
Baseline presence of low-grade dysplasia was associated with progression to HGD/OAC (log rank P<0.001).
p53 immunostaining was significantly associated with shorter progression-free survival (P<0.0001, log rang test; Supplementary Figure 4A).
Low ANXA10 expression was significantly associated with a shorter progression-free survival (P<0.00001, log rank test; Figure 1B).
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