Sentence examples for progression in which from inspiring English sources

The Nkx3.1 Pten mutant mouse model resembles that of human prostate cancer progression in which spontaneous PIN lesions form and progress to adenocarcinomas and eventually hormone refractory tumors upon androgen deprivation.

The evaluation of intraductal approaches for detecting abnormalities has been based on the prevailing model of breast cancer progression, in which epithelial cells lining the ductal lobular systems progress through successive stages of hyperplasia, atypical hyperplasia, carcinoma in situ (DCIS/LCIS), and invasive breast cancer.

It's about life and death and the natural progression in which the young become old, the son rises as the father falters, the protege replaces the mentor.

We thus propose that a functional network composed of OSD1, CYCA1 2/TAM, and TDM controls three key steps of meiotic progression, in which OSD1 is a meiotic APC/C inhibitor.

There takes place a remarkably original, remarkably well-sensed progression in which all three (Ed joins them) drink beer and helped by it advance tentatively out of sales mania, seducer's apathy and victim fear, respectively, to resurrect briefly their alienated selves.

The festival will highlight two new installations of outdoor sculpture: "Irregular Progression," in which Sol LeWitt displays his fascination with geometric progressions and forms derived from dubs, and "Living Chair Trees," two bentwood chairs made by Tom Jahns from tree parts and roots.

Quotations from plainchant are answered by alluring chord progressions in which piercing clusters gradually thin out until only a holistic diatonic harmony remains.

Most epithelial cancers follow a progression scheme in which initiated cells progress to adenomas to adenocarcinomas and metastasis, accumulating genetic alterations in a stepwise manner during progression [6].

Furthermore, von Minckwitz and coworkers [ 49] presented the results of the TBP (Treatment Beyond Progression) trial, in which women who had progressed while on a trastuzumab-based regimen were randomly assigned to treatment with capecitabine monotherapy or capecitabine plus trastuzumab.

Based on our comprehensive study of a relatively large cohort of retinoblastoma cases, we provide evidence for a tumor progression model in which early well-differentiated lesions advance to undifferentiated lesions with higher proliferative capacity.

This refers to as EMT [26] which greatly influences the invasive carcinoma progression and in which the canonical WNT pathway plays a key role.