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At 3 months after SRT, two patients had died of progressive disease: diffuse-invasive and infiltrative progression in one patient and disseminated progression in the other.
One month later the chest X-ray revealed progression in one of pulmonary manifestations, therefore interferon re-induction was initiated based on the hypothetical post-abortion immunological effect and the patient's preference.
Finally, perifosine was found to double the time to progression in one phase II trial for metastatic colon cancer [ 26], but later on failed its phase III clinical trial [ 27, meeting abstract].
Not least because economic conditions vary across the country, so a good rate of progression in one city might be a poor one in another.
Each figure shows the disease progression in one of the graded SD-OCT images, as well as color fundus or Optos® ultra-wide-field images from the corresponding visits.
Sixteen (59%) patients showed histopathologic progression in one or more characteristics.
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Five patients did not complete consolidation chemotherapy because of progressive disease: ascites (one); progression in pancreas (one), liver (one), both pancreas and liver (one), and site not reported (one).
Also, in a study of 5FU-leucovorin in heavily pretreated patients, the change in CA125 levels failed to correlate with measured progression in one-third of the patients (Morgan et al, 1995).
In 2 patients surgical resection was performed as a salvage procedure for disease progressing on IM (primary progession in one case and progression following initial response in another case).
The two experiments are related: they have the same contact listed, and both study diabetes biomarker disease progression in rats (one in liver, and one in adipose tissue).
Elevations may be associated with tumor progression and in one report increased in 100% with progressive NELMs (disease relapse) [ 18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com